MEDICAL: PHARMACY PHARMACEUTICAL PHARMACOLOGY: ANTIBIOTICS :
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Antibiotics Before Age 2 Increases Risk for Childhood Obesity,
Antibiotics Before Age 2 Increases Risk for Childhood Obesity, Study Suggests
March 22, 2016
American Gastroenterological Association
A new study found that administration of three or more courses of antibiotics before children reach an age of 2 years is associated with an increased risk of early childhood obesity.
While early antibiotic use has been associated with a number of rare long-term health consequences, new research links antibiotics to one of the most important and growing public health problems worldwide — obesity. A study1 published online in Gastroenterology, the official journal of the American Gastroenterological Association, found that administration of three or more courses of antibiotics before children reach an age of 2 years is associated with an increased risk of early childhood obesity.
“Our work supports the theory that antibiotics may progressively alter the composition and function of the gut microbiome, thereby predisposing children to obesity as is seen in livestock and animal models,” added Dr. Scott.
Antibiotics are prescribed during an estimated 49 million pediatric outpatient visits per year in the U.S. A large portion of these prescriptions (more than 10 million annually) are written for children without clear indication, despite increased awareness of the societal risks of antibiotic resistance, as well as other tangible risks, including dermatologic, allergic and infectious complications; inflammatory bowel disease; and autoimmune conditions.
Frank I. Scott, Daniel B. Horton, Ronac Mamtani, Kevin Haynes, David S. Goldberg, Dale Y. Lee, James D. Lewis. Administration of Antibiotics to Children Before Age 2 Years Increases Risk for Childhood Obesity. Gastroenterology, 2016; DOI: 10.1053/j.gastro.2016.03.006
The complete article may be read at the URL above.
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