[public-health] MEDICAL: DISEASES: DIABETES : WEIGHT CONTROL : PHYSICAL EXERCISE AND FITNESS : MEDICAL: RESEARCH : WHITE FAT : BROWN FAT : FAT: How Exercise May Turn White Fat Into Brown

 

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MEDICAL: DISEASES: DIABETES :

WEIGHT CONTROL :

PHYSICAL EXERCISE AND FITNESS :

MEDICAL: RESEARCH :

WHITE FAT :

BROWN FAT:

FAT:

How Exercise May Turn White Fat Into Brown

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How Exercise May Turn White Fat Into Brown

Phys Ed

By GRETCHEN REYNOLDS

October 12, 2016

New York Times

http://www.nytimes.com/2016/10/12/well/move/ how-exercise-may-fight-obesity-by-turning-white-fat-into-brown.html

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A shorter URL for the above link:

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http://tinyurl.com/hxubzsj

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Exercise may aid in weight control and help to fend off diabetes by improving the ability of fat cells to burn calories, a new study reports. It may do this in part by boosting levels of a hormone called irisin, which is produced during exercise and which may help to turn ordinary white fat into much more metabolically active brown fat, the findings suggest.

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Irisin (named for the Greek goddess Iris) entered the scientific literature in 2012 after researchers from Harvard and other universities published a study in Nature that showed the previously unknown hormone was created in working muscles in mice. From there, it would enter the bloodstream and migrate to other tissues, particularly to fat, where it would jump-start a series of biochemical processes that caused some of the fat cells, normally white, to turn brown.

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Brown fat, which is actually brown in color, burns calories. It also is known to contribute to improved insulin and blood sugar control, lessening the risk for Type 2 diabetes. Most babies, including human infants, are plump with brown fat, but we humans lose most of our brown fat as we grow up. By the time we are adults, we usually retain very little brown fat.

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In the 2012 study, the researchers reported that if they injected irisin into living mice, it not only turned some white fat into brown fat, it apparently also prevented the rodents from becoming obese, even on a high-fat, high-calorie diet.

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But in the years since, some scientists have questioned whether irisin affects fat cells in people to the same extent as it seems to in mice  and even whether the hormone exists in people at all.

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A study published last year in Cell Metabolism by the same group of researchers who had conducted the first irisin study, however, does seem to have established that irisin is produced in humans. They found some irisin in sedentary people, but the levels were much higher in those who exercise often.

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But whether irisin acted beneficially in human fat cells the same way as it did in the bodies and cells of mice was still an open and disputed question.

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The complete article may be read at the URL above.

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Sincerely,
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[public-health] MEDICAL: DISEASES: DIABETES : WEIGHT CONTROL : PHYSICAL EXERCISE AND FITNESS : MEDICAL: RESEARCH : WHITE FAT : BROWN FAT : FAT: How Exercise May Turn White Fat Into Brown

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